The Relationship Between Side Effects of Anti-Tuberculosis Drugs (OATs) with Drug Compliance in Pulmonary TB Patients at the Paal V Health Center in Jambi City in 2024

Hisran Hisran; Iisma Rizki Fadhila

doi:10.35910/icohpj.v3i0.885

Hisran Hisran Department of Pharmacy, Politeknik Kesehatan Kementerian Kesehatan Jambi, Indonesia
Iisma Rizki Fadhila Department of Pharmacy, Politeknik Kesehatan Kementerian Kesehatan Jambi, Indonesia

DOI: https://doi.org/10.35910/icohpj.v3i0.885

Keywords: Tuberculosis, Anti-Tuberculosis Drugs, Side effects, Adherence to taking medicine

Abstract

Background: Tuberculosis (TB) is a disease caused by Mycrobacterium Tuberculosis. One of the factors causing the low cure rate is non-compliance in the treatment of TB patients. This is due to the side effects of TB drugs so some patients choose to stop taking anti-tuberculosis drugs. This study aims to analyze the relationship between the side effects of antituberculosis drugs
(OAT) and drug compliance in pulmonary TB patients at the Puskesmas.
Methods: Quantitative research with a cross-sectional approach. Sampling using a total sampling technique where the number of pulmonary TB patients was 30 people. The instrument used for OAT side effects was a questionnaire that had been used before and the questionnaire for drug compliance used a valid and reliable questionnaire from MMAS, then the data were analyzed univariately and bivariately with the Chi-square test and Fisher's test.
Results: Most of the respondents experienced mild side effects as much as (86.7%) and most of the respondents were compliant in taking the drug as much as (46.7%) from the results of the analysis obtained the value of the OAT side effect variable p-value = 0.039 (<0.05).
Conclusion: They concluded that there is a relationship between the side effects of anti-tuberculosis drugs (OAT) and adherence to taking medication in pulmonary TB patients. Respondents in this study had good compliance despite mild or severe side effects.